Friday, March 27, 2009

Muscle soreness and My cholesterol Medication

I have been on been on Simstatin a statin cholesterol lowering med since mid December. I recently had heard from another ultra runner that he stopped taking statins because of muscle soreness. I has heard that that was a possible- but low incident side effect and a person was to let their physician know immediately if they had any unexplainable soreness.
Well being a runner I get sore and being a person who is getting older- well who is to say what is explainable and what is not.
Wednesday eve I did a 25K loop out at Afton. I could not believe how totally sore I was, it started before 10 miles even and lasted even after I stopped running and into the evening. Actually Saturday for my 26 miles at Afton I was very sore early on also. I was very sore in my 50 mile race- actually probably earlier than I would have thought- sore in my teens rather than progressively later in the race. Hum.. I have been having some leg cramping and some other aches and pains also, something I never had alot of but again with my milage lately probably wouldn't think much of it either.
So yesterday I started an Internet search to try to find some answers. It turns out that the muscle soreness is a very real especially for athletes. There was this study of like 22 female athletes who had the family induced type high cholesterol and they went through all the different statins and it ended up all but 3 I think it was could tolerate continuing. There is also something that the statins blocks production of in the liver that is used for your muscles to be not broken down.
Rhabdomyolysis is something that can happen if the muscle breakdown were to the extreme and it can even be deadly. One woman ignored her muscle pain and did an event of some kind anyway with really bad results. (hum..would this be like continuing on during a 100 mile race while you felt like your muscles were already at their breaking point).
I had also the results from my blood test last week an my cholesterol was down some but my liver test was slightly elevated ALT(SGPT)-not sure what it means can't find anything about if elevated liver whatever is bad for an ultrarunner?.
Short story- I have stopped taking the cholesterol med and will hope I am OK for my 100 mile race in two weeks.
Since I just stopped my first dosage last night I really don't know how hard I should work out this week. I was planning on getting in abaout 30-40 tomorrow but I am sort of freaked out now.


Blogger SteveQ said...

If it's rhabdomyolysis, your urine turns brown; you couldn't mistake it. You shouldn't stop a medicine before talking to your doctor about it first, though stopping statins usually isn't a problem.

March 27, 2009 at 10:10 AM  
Anonymous Anonymous said...

Google Dr. Duane Graveline's web site: to read about the various mechanisms responsible for muscle difficulties due to statins, then read the forum feature for statin sufferers' accounts of damage these individuals feee is wrought by this class of drugs.

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